منابع مشابه
Up to Date Gastric Cancer Surgery
BACKGROUND: Effective palliation rather than cure is often the most appropriate goal in the management of patients with advanced gastric cancer.The literature to date is limited by the imprecise use of the term palliative and subsequent variable designation of patients into evaluable groups. STUDY DESIGN: Between 2000 and 2007, 303 patients underwent a operation for gastric adenocarcinoma. Pati...
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Ovarian cancer is the first cause of death from gynaecological malignancy. Germline mutation in BRCA1 and 2, two genes involved in the mechanisms of reparation of DNA damage, are showed to be related with the incidence of breast and ovarian cancer, both sporadic and familiar. PARP is a family of enzymes involved in the base excision repair (BER) system. The introduction of inhibitors of PARP in...
متن کاملAn Up-to-Date Anti-Cancer Treatment Strategy Focusing on HIF-1α Suppression: Its Application for Refractory Ovarian Cancer
Hypoxia inducible factor-1alpha (HIF-1alpha) predominantly determines the transcriptional activity of HIF-1, which induces the certain genetic expressions to participate in the proliferation and progression of the tumor. It is supposed that HIF-1alpha is also an extremely important factor in cancer treatment. Based on the results of our recent analyses using ovarian tumors, which indicated the ...
متن کاملSurvival from cancer--up-to-date predictions using period analysis.
OBJECTIVES This period analysis provides Canadian predictions of the short- and long-term relative survival of people recently diagnosed with cancer. Long-term period and cohort-based estimates are also compared. DATA SOURCES Data are from the Canadian Cancer Registry, the Canadian Mortality Data Base, and Statistics Canada life tables. ANALYTICAL TECHNIQUES Relative survival analyses were ...
متن کاملImmunotherapy of Cancer — Some Up-To-Date Approaches
Treatment of cancer is currently based on three main modalities: surgery, radiothera‐ py and chemotherapy. Most solid tumours can only be cured at an early stage, due to the lack of effective systemic treatment. Surgery and radiotherapy are highly effective for eradicating localized tumours, but unfortunately cannot target disseminated dis‐ ease. Chemotherapy represents systemic treatment, but ...
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ژورنال
عنوان ژورنال: Chinese Clinical Oncology
سال: 2020
ISSN: 2304-3865,2304-3873
DOI: 10.21037/cco-2019-oc-13